Author

Haruko Takeda

University of LiègeORCID 0000-0002-8455-6887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Michel GeorgesiD· 4 shared Latifa Karim· 3 shared Wouter R. CoppietersiD· 3 shared Carole CharlieriD· 2 shared Gabriel Costa Monteiro MoreiraiD· 2 shared Tom DruetiD· 2 shared A.C. BouwmaniD· 1 shared Alex Kvasz· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Michel GeorgesORCID

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4 papers

Recent·Most cited

Integrated cell type-specific analysis of blood and gut identifies matching eQTL for 140 IBD risk loci and entrectinib as possible repurposing candidate.

Hélène Perée, В. А. Петров, Yumie Tokunaga, Alex Kvasz, Sophie Vieujean, Sarah Regimont, Myriam Mni, Marie Wéry, Samira Azarzar, Sophie Jacques, Nicolas Fouillien, Latifa Karim, Manon Deckers, Émilie Detry, Alice Mayer, , Souad Rahmouni

The paper identifies 140 IBD risk loci with matching eQTL in blood and gut tissues and suggests entrectinib as a potential repurposing drug.

medRxiv · Oct 14, 2024 · PreprintGenetic & Genomic Medicine

Sequenced-based GWAS for linear classification traits in Belgian Blue beef cattle reveals new coding variants in genes regulating body size in mammals

José Luis Gualdrón Duarte, Can Yuan, Ann-Stephan Gori, Gabriel Costa Monteiro Moreira, Haruko Takeda, Wouter R. Coppieters, Carole Charlier, Michel Georges, Tom Druet

This study performs a GWAS on Belgian Blue beef cattle to identify coding variants associated with body size and muscular development, finding new genes and variants linked to growth in mammals.

Genetics Selection Evolution · Nov 28, 2023Peer-reviewedGenetics

A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle

Young-Lim Lee, Haruko Takeda, Gabriel Costa Monteiro Moreira, Latifa Karim, Erik Mullaart, Wouter R. Coppieters, Ruth Appeltant, Roel F. Veerkamp, Martien A. M. Groenen, Michel Georges, Mirte Bosse, Tom Druet, A.C. Bouwman, Carole Charlier

The paper identifies a 12 kb multi-allelic CNV associated with mastitis resistance in dairy cattle by linking it to increased GC expression and a cis-regulatory enhancer.

PLoS Genetics · Jul 21, 2021Peer-reviewedGenomics

Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals putative regulatory toggles operating in native and iPS-derived retina.

Anouk Georges, Arnaud Lavergne, Michiko Mandai, Fanny Lepiemme, Latifa Karim, Loic Demeulenaere, Diego Aguilar, Michael Schyns, Sébastien Dupont, Laurent Nguyen, Jean-Marie Rakic, Masayo Takahashi, Michel Georges, Haruko Takeda

The paper analyzes single-cell RNA-Seq and ATAC-Seq data from native and iPSC-derived murine retina to identify regulatory toggles involved in differentiation.

bioRxiv · Mar 2, 2020 · PreprintDevelopmental Biology