Carole Charlier

The paper presents a reusable TWAS workflow for cattle to identify gene-trait associations using GWAS and transcriptomic data, improving variant calling and detecting novel associations.

The study identifies miRNA polymorphisms in goats, finding low variation in seed regions due to purifying selection and higher variation in regulatory regions of isolated populations.

This study identifies reliable circular RNAs in bovine tissues by comparing total-RNAseq and mRNAseq data, revealing many artificial circRNAs and false entries in existing catalogs.

This study performs a GWAS on Belgian Blue beef cattle to identify coding variants associated with body size and muscular development, finding new genes and variants linked to growth in mammals.

The paper annotates transcription start sites and enhancers in cattle using CAGE sequencing across multiple tissues and populations to improve genome annotation and inform breeding programs.

The paper tests for transgenerational epigenetic effects of non-transmitted paternal alleles in mice and finds no significant evidence of such effects on gene expression or anatomical traits.

The paper characterizes the spatiotemporal H3K27ac landscape in pigs to identify regulatory elements and their associations with gene regulation and complex traits.

The paper identifies a 12 kb multi-allelic CNV associated with mastitis resistance in dairy cattle by linking it to increased GC expression and a cis-regulatory enhancer.

PCIP-seq uses long-read sequencing to simultaneously identify retroviral insertion sites and their integrated proviruses, revealing SNPs, structural variants, and viral evolution.

Cattle pedigrees indicate up to ~30% of de novo mutations in male gametes and ~50% in female gametes arise during early cleavage divisions, leaving parental mosaicism and sibling sharing.