Jason Liu

This study shows that DSPE-PEG fails to retain mAbs on LNPs in vivo, while a higher molecular weight PCL-b-PEG anchor maintains stability, highlighting the importance of anchoring strength for extrahepatic delivery.

The paper introduces a framework to compare and aggregate outputs from multiple Active Module Identification algorithms in genetic interaction networks, finding that no single algorithm performs well across datasets and proposing methods to combine results.