Author

Rasmus Siersbæk

University of CambridgeORCID 0000-0002-8481-2182Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alasdair Russell· 1 shared Anne PajoniD· 1 shared Chandra Sekhar Reddy ChilamakuriiD· 1 shared Christian Dalager Vaagensø· 1 shared Florian T. MerkleiD· 1 shared Hjörleifur EinarssoniD· 1 shared Jason S. CarrolliD· 1 shared Maria S. MadseniD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenomics

Alasdair Russell

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MYC enhancer invasion promotes prognostic cancer type-specific gene programs through an epigenetic switch

Simon T. Jakobsen, Rikke AM. Jensen, Tina Ravnsborg, Christian Dalager Vaagensø, Hjörleifur Einarsson, Maria S. Madsen, Robin Andersson, Ole Nørregaard Jensen, Rasmus Siersbæk

The paper shows MYC enhances cancer-specific gene programs by inducing an epigenetic switch that promotes RNAPII recruitment to enhancers.

bioRxiv · Jan 6, 2023 · PreprintGenomics

GenEditID: an open-access platform for the high-throughput identification of CRISPR edited cell clones

Ying Xue, Y. C. Loraine Tung, Rasmus Siersbæk, Anne Pajon, Chandra Sekhar Reddy Chilamakuri, Rubén Álvarez-Fernández, Richard Bowers, Jason S. Carroll, Matthew Eldridge, Alasdair Russell, Florian T. Merkle

GenEditID is a platform for identifying CRISPR-edited cell clones using deep sequencing and proteomic data, enabling scalable and sensitive gene editing analysis.

bioRxiv · Jun 13, 2019 · PreprintGenomics