Author

Philipp Pracht

University of CambridgeORCID 0000-0002-8495-9504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aakrosh RataniD· 1 shared Ahmed AlmaghasilahiD· 1 shared Bryce M. PaschaliD· 1 shared Chunsong YangiD· 1 shared David J. WalesiD· 1 shared Dmitri V. FilippoviD· 1 shared Jack MasuriD· 1 shared Joshua B. KelleyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aakrosh RatanORCID

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1 paper

Recent·Most cited

Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling

Krzysztof Wierbiłowicz, Chunsong Yang, Ahmed Almaghasilah, Patryk Adam Wesołowski, Philipp Pracht, Natalia M. Dworak, Jack Masur, Sven Wijngaarden, Dmitri V. Filippov, David J. Wales, Joshua B. Kelley, Aakrosh Ratan, Bryce M. Paschal

The paper identifies PARP7 as an enzyme that ADP-ribosylates the androgen receptor, marking it for degradation and creating negative feedback on AR-dependent gene expression.

The EMBO Journal · Jul 18, 2025Peer-reviewedCancer Biology