Cancer BiologyEuropean Journal of Cell BiologyPeer-reviewed
Dual Pathways of Extracellular ATP Action in Cancer Cells: Purinergic Signaling Driven Senescence and Macropinocytic ATP Internalization
Nicole Stone, Ryan A. Ward, Lindsey M. Bachmann…·Xiaozhuo Chen
This study identifies two pathways by which extracellular ATP affects cancer cells: macropinocytic uptake increasing intracellular ATP and purinergic receptor signaling inducing senescence.
DOI 10.1016/j.ejcb.2026.151583