Author

Xiaozhuo Chen

Ohio UniversityORCID 0000-0001-9635-4572Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Corinne M. NielseniD· 2 shared Dennis A. Roberts· 2 shared Haiyun ZhangiD· 2 shared Jingwen SongiD· 2 shared Lindsey M. Bachmann· 2 shared Pratik ShriwasiD· 2 shared Ryan A. WardiD· 2 shared Stephen C. BergmeieriD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Corinne M. NielsenORCID

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2 papers

Recent·Most cited

Cancer BiologyEuropean Journal of Cell BiologyPeer-reviewedOct 1, 2026

Dual Pathways of Extracellular ATP Action in Cancer Cells: Purinergic Signaling Driven Senescence and Macropinocytic ATP Internalization

Nicole Stone, Ryan A. Ward, Lindsey M. Bachmann…·Xiaozhuo Chen

This study identifies two pathways by which extracellular ATP affects cancer cells: macropinocytic uptake increasing intracellular ATP and purinergic receptor signaling inducing senescence.

DOI 10.1016/j.ejcb.2026.151583

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintDec 15, 2024

A novel pan class-I glucose transporter inhibitor DRB18 exhibits synergistic effects in vitro and in vivo with paclitaxel against human non-small cell lung cancer

Pratik Shriwas, Lindsey M. Bachmann, Ryan A. Ward…·Xiaozhuo Chen

This study shows that DRB18, a pan-class I GLUT inhibitor, synergizes with paclitaxel to reduce NSCLC cell proliferation in vitro and tumor growth in vivo.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky