Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice
Emanuel J. Novais, Olivia K. Ottone, Eric V. Brown, Vedavathi Madhu, Victoria A. Tran, Pranay L. Ramteke, Abhijit S. Dighe, Michael D. Solga, Alexandra Manchel, Angelo C. Lepore, Makarand V. Risbud
This study identifies SM/J mice as a model for spontaneous disc herniations and shows neuroimmune changes drive chronic discogenic pain.
Science Advances · Apr 23, 2025Peer-reviewedCell Biology