Józef Romuald Lewandowski

This study characterizes SidG, a GNAT enzyme in Aspergillus fumigatus, revealing its iterative acetylation mechanism for siderophore biosynthesis.

The paper identifies a novel subunit docking mechanism in depsipeptide HDAC inhibitor biosynthesis using gene proximity searching and experimental validation.

This paper develops an esterase-mediated strategy to generate unstable substrates for EpnF, revealing its broad substrate tolerance and catalytic mechanism for epoxyketone synthesis.

The paper characterizes the AT:ACP interface in a fungal polyketide synthase using mutagenesis, mass spectrometry, and simulations to reveal structural and functional insights.

This study shows BiP directly interacts with Ire1 oligomers to regulate its activation, controlling ER stress response by modulating Ire1-LD oligomerization.