Constance Q. Zhou

This study shows that TDP-43 mutations in ALS/FTD reduce HSV-1 infection by disrupting cell-adhesion pathways and impairing viral entry.

The paper shows astrocytic GPCR signaling affects spatial memory differently in male and female mice, with opposing effects on memory based on receptor type and sex.

This study shows that TDP-43 accumulation in astrocytes impairs memory by altering antiviral pathways and chemokine signaling between astrocytes and neurons.