Steven L. Spitalnik

This study identifies molecular and cellular changes in storage-induced senescent erythrocytes (SMEs) that lead to their clearance, showing altered metabolism, proteostasis, and membrane properties.

This study examines the association between hematocrit levels and dementia risk in a multiethnic cohort, finding that lower hematocrit is linked to increased dementia risk, with no mediation by cerebral small vessel disease.

This study identifies Steap3 as a regulator of ferroptosis-like lipid peroxidation in stored RBCs, linking genetic variants to hemolysis in mice and human blood donors.