Author

Eero V. Hietanen

University of LeedsORCID 0000-0002-8548-3990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

David J. RowlandsiD· 3 shared Nicola J. StonehouseiD· 3 shared Natalie J. KingstoniD· 2 shared P. K. HalliD· 2 shared Ana Carolina Gomes JardimiD· 1 shared Connor HaywardiD· 1 shared David J. FilmaniD· 1 shared James M. HogleiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

David J. RowlandsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologyJournal of General VirologyPeer-reviewedDec 17, 2025

Development of enterovirus trans-encapsidation assays as tools to understand viral entry.

P Hall, Natasha Marques Cassani, Eero V. Hietanen…·Nicola J. Stonehouse

This paper develops trans-encapsidation assays to study enterovirus entry, uncoating, and replication using reporter replicons and structural proteins expressed in trans.

DOI 10.1099/jgv.0.002196

humanproteomics

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 17, 2025

Interactions between the 2C protein of FMDV and components of the viral replication machinery are mediated by ER-derived membranes

Connor Hayward, Eero V. Hietanen, Samuel J. Dobson…·Nicola J. Stonehouse

This study identifies interactions between FMDV 2C protein and viral and host factors, revealing ER-derived replication complexes and potential targets for disrupting the FMDV lifecycle.

DOI 10.1101/2025.09.17.676763

proteomicsexperimental assay

𝕏 PostBluesky

MicrobiologyPLoS PathogensPeer-reviewedSep 19, 2024

Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.

Natalie J. Kingston, Joseph S. Snowden, Keith Grehan…·Nicola J. Stonehouse

The paper determines the molecular mechanism of VP0 cleavage in enteroviruses using structural and bioinformatic analysis of a provirion intermediate.

13 citations

structural biologybiophysical modeling

𝕏 PostBluesky