Author

Samuel J. Dobson

University of LeedsORCID 0000-0002-8815-7381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

David J. RowlandsiD· 3 shared Morgan R. HerodiD· 3 shared Nicola J. StonehouseiD· 3 shared Joseph C. WardiD· 2 shared Andrew TupliniD· 1 shared Christopher W. WassoniD· 1 shared Connor HaywardiD· 1 shared Donald P. KingiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMolecular Biology

David J. RowlandsORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 30, 2026

Chikungunya virus live-cell reporter systems reveal cell-type-dependent antiviral responses to ribavirin

Samuel J. Dobson, Molly G. A. Brereton, Lai Wei…·Andrew Tuplin

This study develops live-cell CHIKV reporter systems to analyze cell-type-dependent antiviral responses to ribavirin, revealing differences in antiviral efficacy across cell models.

DOI 10.64898/2026.10.27.762381

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 17, 2025

Interactions between the 2C protein of FMDV and components of the viral replication machinery are mediated by ER-derived membranes

Connor Hayward, Eero V. Hietanen, Samuel J. Dobson…·Nicola J. Stonehouse

This study identifies interactions between FMDV 2C protein and viral and host factors, revealing ER-derived replication complexes and potential targets for disrupting the FMDV lifecycle.

DOI 10.1101/2025.09.17.676763

proteomicsexperimental assay

𝕏 PostBluesky

Molecular BiologyThe FASEB JournalPeer-reviewedJul 28, 2024

The dual role of a highly structured RNA (the S fragment) in the replication of foot-and-mouth disease virus.

Joseph C. Ward, Lidia Lasecka‐Dykes, Samuel J. Dobson…·Nicola J. Stonehouse

This study investigates the role of the conserved S fragment in FMDV replication using SHAPE and genomic analyses, revealing its structural importance and interaction with 3Dpol.

3 citations

experimental assay

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Molecular BiologyJournal of General VirologyPeer-reviewedJul 12, 2023

A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis-acting elements in foot-and-mouth disease virus replication

Samuel J. Dobson, Joseph C. Ward, Morgan R. Herod…·Nicola J. Stonehouse

The paper introduces a method to distinguish viral RNA strands and investigates the role of cis-acting elements in FMDV replication.

4 citations

experimental assay

𝕏 PostBluesky