Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling
Anne‐Xander van der Stel, Emily R. Gordon, Arnab Sengupta, Allyson K. Martínez, Dorota Klepacki, Thomas N. Perry, Alba Herrero del Valle, Nora Vázquez‐Laslop, Matthew S. Sachs, Luis Rogelio Cruz-Vera, C. Axel Innis
The paper investigates how the TnaC-ribosome complex recognizes and responds to L-Trp, revealing a mechanism involving cleavage rates and ligand binding.
Nature Communications · Sep 9, 2021Peer-reviewedMolecular Biology