C. Axel Innis

The paper identifies how tetracenomycin X inhibits bacterial translation by sequestering peptidyl-tRNA at QK motifs, revealing a novel mechanism for antibiotic action.

The paper investigates how the TnaC-ribosome complex recognizes and responds to L-Trp, revealing a mechanism involving cleavage rates and ligand binding.

This study introduces inverse toeprinting to map ribosome arrest sites on mRNA and identifies sequence-specific arrest motifs for ribosome-targeting antibiotics.