Cancer BiologybioRxivPreprint
CDK4/6 Inhibition Reverses MEIS2 Suppression of CRL4 to Enhance Immunomodulatory Drug Therapy in Multiple Myeloma
Xiangao Huang, David S. Jayabalan, Maurizio Di Liberto…·Selina Chen‐Kiang
This paper shows CDK4/6 inhibition enhances immunomodulatory drug therapy in multiple myeloma by reversing MEIS2 suppression of CRL4CRBN and reducing BCMA signaling.
DOI 10.1101/2025.10.14.681840