Laia Alegre-Zurano

Lack of rhythmicity in Bmal1 deficient mice impairs motivation towards natural stimuli.

This study shows that Bmal1 deficiency disrupts circadian rhythms and alters reward-related gene expression, leading to increased motivation for natural rewards in mice.

Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition

This study shows that a single cocaine dose impairs eCB-LTD and social behavior in mice, which can be reversed by FAAH inhibition.

The FAAH inhibitor URB597 reduces cocaine seeking during conditioned punishment and withdrawal

Bmal1-knockout mice exhibit reduced cocaine-seeking behaviour and cognitive impairments

This study examines Bmal1-knockout mice, finding reduced cocaine-seeking behavior and cognitive impairments linked to altered dopamine metabolism.

Cannabidiol effects on cocaine-seeking behaviour and incubation of craving in mice.

This paper develops a mouse model to study cocaine-seeking behavior and incubation of craving, finding that cannabidiol reduces cocaine self-administration but not craving incubation, depending on administration timing.

The effects of cannabidiol on cue- and stress-induced reinstatement of cocaine seeking behavior in mice are reverted by the CB1 receptor antagonist AM4113.

This study investigates cannabidiol's effects on cocaine seeking behavior in mice, finding it blocks cue-induced reinstatement but facilitates stress-induced reinstatement, with CB1 receptor involvement.