Salvador Aznar Benitah

This study identifies NGFR as a regulator of immune evasion in HNSCC, showing that its inhibition enhances antigen presentation and CD8+ T cell response to checkpoint blockade.

This study shows that the central clock controls metabolic rhythms in muscle stem cells, independent of the local stem cell clock, and highlights the role of autophagy and lipid metabolism in this process.

This study identifies a BMAL1-YAP transcriptional complex that hijacks enhancers in aged epidermis to promote inflammation by rewiring chromatin dynamics and co-regulating inflammation-related genes with NF-KB.

The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.

This study shows that Bmal1 deficiency disrupts circadian rhythms and alters reward-related gene expression, leading to increased motivation for natural rewards in mice.

This study examines Bmal1-knockout mice, finding reduced cocaine-seeking behavior and cognitive impairments linked to altered dopamine metabolism.