Olivier J. Manzoni

This study uses automated analysis to show that prenatal CBD and THC exposure leads to distinct effects on maternal retrieval behavior in mice, with compound-specific changes in kinematics and learning.

This study examines sex-specific effects of prenatal CBD and THC exposure on adult mouse behavior and prefrontal cortex circuitry, revealing distinct synaptic and behavioral outcomes.

This study examines how prenatal exposure to THC and CBD affects medial prefrontal cortex circuitry in adult mice, revealing compound- and sex-specific changes in excitability and synaptic plasticity.

This study shows prenatal exposure to CBD or THC alters adult offspring behavior differently by sex, with CBD increasing female risk assessment and both increasing repetitive behavior.

This study shows prenatal CBD exposure causes sex-specific anxiety disruptions in mice, with females showing persistent anxiety-like behaviors and altered reward responsiveness.

This study examines how prenatal CBD exposure affects the insular cortex in adult mice, revealing sex- and territory-specific disruptions in neuronal properties.

This study examines sex differences in synaptic properties and neuronal characteristics across subregions of the mouse insular cortex, revealing distinct features in excitability, synaptic strength, and plasticity.

This study shows that a single cocaine dose impairs eCB-LTD and social behavior in mice, which can be reversed by FAAH inhibition.

This study investigates synaptic deficits in the prefrontal cortex of Ts65Dn mice, a model for Down syndrome, and compares them to mBACtgDyrk1a mice, revealing differences in synaptic plasticity and intrinsic neuronal properties.

This study investigates synaptic dysfunction in the BLA-NAcC pathway of FXS mice, finding increased synaptic strength and altered plasticity in specific SPN subtypes.

The paper examines how in utero CBD exposure affects early-life behaviors in mice, finding sex-specific changes in weight, homing behavior, and vocalizations.

The paper compares intrinsic properties of D1- and D2-MSNs in FXS mice and finds they lose their distinct characteristics, leading to a uniform phenotype.

This study identifies sex-specific differences in the maturation of BLA neurons and synaptic properties in rats during adolescence and adulthood.

This study shows that adolescent cannabinoid exposure reduces prefrontal reelin expression and impairs synaptic plasticity, mimicking reelin haploinsufficiency.

This study identifies sex-specific developmental differences in endocannabinoid-mediated LTD in rat prefrontal cortex, showing distinct receptor usage and timing of eCB-LTD emergence between males and females.

This study shows that THC exposure via lactation during early postnatal life leads to lasting behavioral and synaptic deficits in adult rats.

The paper examines synaptic connectivity and plasticity in the adult mouse nucleus accumbens core, revealing pathway- and cell-type specific contributions of BLA, PFC, and vHipp inputs, and the role of endocannabinoid receptors.

This study examines sex differences in behavioral and synaptic effects of a single cannabinoid exposure at puberty and adulthood in rats.

This study investigates sex-specific behavioral and neuronal deficits in adult rats exposed to prenatal cannabinoids, finding differences in social interaction, synaptic plasticity, and receptor expression between males and females.

This study shows that maternal cannabinoid exposure during lactation delays the GABA switch in prefrontal cortex neurons of rat offspring via a CB1R-dependent mechanism.

This study examines how muscarinic M1 receptor activation affects synaptic plasticity in the nucleus accumbens of wild-type and fragile X mice, revealing distinct mechanisms and deficits in the latter.