Author

Benita Kiat Tee Tan

Singapore General HospitalORCID 0000-0002-8573-4606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Ann S. G. LeeiD· 1 shared Anna GaniD· 1 shared Chih Chuan Shih· 1 shared Danliang HoiD· 1 shared Dimitrios KleftogiannisiD· 1 shared Gek San Tan· 1 shared Iain Beehuat TaniD· 1 shared Jean-Michel CarteriD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Ann S. G. LeeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in Triple-Negative Breast Cancer

Nicholas Sim, Jean-Michel Carter, Kamalakshi Deka, Benita Kiat Tee Tan, Yirong Sim, Suet‐Mien Tan, Yinghui Li

This study shows that TWEAK/Fn14 signalling rewires the transcriptomic and epigenomic landscape of TNBC, promoting metastasis through super-enhancer-driven metabolic reprogramming.

Nature Communications · Jul 5, 2024Peer-reviewedCancer Biology

Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing

Dimitrios Kleftogiannis, Danliang Ho, Jun Xian Liew, Polly S. Y. Poon, Anna Gan, Raymond Chee-Hui Ng, Benita Kiat Tee Tan, Kiang Hiong Tay, Swee Ho Lim, Gek San Tan, Chih Chuan Shih, Tony Kiat Hon Lim, Ann S. G. Lee, Iain Beehuat Tan, Yoon Sim Yap, Sarah Boon Hsi Ng

This paper develops a targeted cfDNA sequencing approach for detecting genomic alterations in breast cancer using UMIs and bioinformatics pipelines, showing high concordance with tumor sequencing.

Scientific Reports · Oct 8, 2020Peer-reviewedGenomics