Cancer BiologyNature CommunicationsPeer-reviewed
TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in Triple-Negative Breast Cancer
Nicholas Sim, Jean-Michel Carter, Kamalakshi Deka…·Yinghui Li
This study shows that TWEAK/Fn14 signalling rewires the transcriptomic and epigenomic landscape of TNBC, promoting metastasis through super-enhancer-driven metabolic reprogramming.
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