Author

Gary H. Cohen

University of PennsylvaniaORCID 0000-0002-8581-8068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Doina AtanasiuiD· 2 shared Tina M. CairnsiD· 2 shared Wan Ting Saw· 2 shared Adam CahilliD· 1 shared Ahmed A. Belghith· 1 shared Antonio N. CalabreseiD· 1 shared Bernard MossiD· 1 shared Catherine A. CotteriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Doina AtanasiuORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Unveiling the unique interaction mechanism of herpes simplex virus 2 glycoprotein C with C3b

Moisés H. Rojas-Rechy, Doina Atanasiu, Lauren M. Hook, Tina M. Cairns, Wan Ting Saw, Adam Cahill, Zilin Guo, Antonio N. Calabrese, Neil A. Ranson, Harvey M. Friedman, Gary H. Cohen, Juan Fontana

This study determines the structure of herpes simplex virus 2 glycoprotein C interacting with C3b, revealing a unique mechanism to modulate the complement cascade.

Communications Biology · Aug 4, 2026Peer-reviewedMolecular Biology

Antibody Binding and Neutralizing Targets within the Predicted Structure of the Poxvirus Multiprotein Entry-Fusion Complex

Huibin Yu, Wolfgang Resch, Catherine A. Cotter, Wei Xiao, Tase Karamanolis, Ahmed A. Belghith, Maxinne A. Ignacio, Patricia L. Earl, Gary H. Cohen, Bernard Moss

The paper identifies two novel targets in the poxvirus EFC that induce cross-neutralizing antibodies and offers insights into immune evasion strategies.

bioRxiv · May 7, 2025 · PreprintMicrobiology

Allosteric mechanism of membrane fusion activation in a herpesvirus

Gonzalo L. González‐Del Pino, Richard M. Walsh, Doina Atanasiu, Tina M. Cairns, Wan Ting Saw, Gary H. Cohen, Ekaterina E. Zheleznova Heldwein

This study determines the pre-activation structure of the herpesvirus gH/gL complex and identifies an allosteric mechanism for transmitting fusion signals from gD to gB.

bioRxiv · Sep 20, 2024 · PreprintMicrobiology