Philipp J. Kahle

This study shows that parkin-dependent ubiquitination of TAX1BP1's CC3 domain is not essential for mitophagy but reroutes degradation to a less efficient endolysosomal pathway when CC3 is absent.

This study shows LAG3 is not expressed in human and mouse neurons and does not worsen α-synuclein pathology in vitro or in vivo.

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.