Lars Eijssen

User-friendly transcriptomic data analysis with ArrayAnalysis

ArrayAnalysis provides an interactive web and desktop platform for analyzing microarray and RNA-seq data, offering tools for preprocessing, differential expression, and visualization to support both novice and expert users.

Epigenomic subtypes of late-onset Alzheimer's disease reveal distinct microglial signatures

This study identifies two epigenomic subtypes of late-onset Alzheimer's disease with distinct microglial and neuronal methylation signatures, linking them to different inflammatory and functional pathways.

Blood-based multivariate methylation risk score for cognitive impairment and dementia

The paper develops a multivariate methylation risk score using blood DNA methylation data to predict dementia risk and cognitive impairment in Alzheimer's and Parkinson's disease cohorts.

COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms

The paper describes the development of a computational knowledge repository, the COVID-19 Disease Map, which curates SARS-CoV-2 virus-host interaction mechanisms and provides tools for their analysis and application.

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

The paper integrates transcriptome data from human cells with impaired MECP2 to identify a network of genes involved in Rett syndrome and their regulatory mechanisms.