Akira Yamaoka

Ductal myofibroblasts reactivate contractile program to stabilize alveolar architecture during lung regeneration

The paper identifies ductal myofibroblasts as critical for maintaining alveolar structure during lung regeneration through reactivation of a contractile program.

Airway tissue stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration

This study identifies the Tgfβ-Id2 axis as a regulator of proliferation transitions in airway basal cells during development and regeneration, showing its role in tissue repair and potential in preventing hyperplasia.

Bidirectional Wnt signaling between endoderm and mesoderm confer tracheal identity in mouse and human.

This study identifies bidirectional Wnt signaling between endoderm and mesoderm as critical for tracheal identity in mouse and human, with implications for tissue repair.

Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus

The paper investigates the mechanisms regulating trachea and esophagus development in mice, showing that radial cell polarization and cartilage development control tube elongation and diameter.