Mitsuru Morimoto

The paper identifies and characterizes a new population of early hepatoblasts in mouse and human liver development, showing their role in liver bud formation and their decline in later stages.

The paper uses single-cell transcriptomics to map endoderm-mesoderm interactions during foregut organogenesis and validates signaling pathways in mice, then generates mesoderm subtypes from human pluripotent stem cells.

This study identifies bidirectional Wnt signaling between endoderm and mesoderm as critical for tracheal identity in mouse and human, with implications for tissue repair.

The paper investigates the mechanisms regulating trachea and esophagus development in mice, showing that radial cell polarization and cartilage development control tube elongation and diameter.

This study identifies KCNJ13 as critical for tracheal tubulogenesis by maintaining ion homeostasis and actin polymerization in smooth muscle cells.