Nicole A. Kochan

The paper examines associations between grey matter volumes and white matter hyperintensities with cognitive empathy measures in oldest-old adults, finding significant links between specific brain regions and different empathy assessment methods.

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

This study identifies genetic resilience factors for Alzheimer's disease by constructing polygenic resilience scores that reduce genetic risk penetrance and correlate with polygenic risk scores in unaffected individuals.

This study examines age-related changes in PSMD across the adult lifespan using multi-cohort diffusion tensor imaging data, finding PSMD increases consistently while other metrics show different age patterns.

This study uses personalized Virtual Brain models to show that local and global brain dynamics correlate with cognitive differences in Alzheimer’s disease and related conditions.

This study identifies three latent patterns linking age, education, and functional brain networks in healthy older adults, showing age affects core cognitive processes while education influences distinct networks.