Jiyang Jiang

Unified Multi-Cohort Harmonisation and Normative Modelling of Neuroimaging Data via Hierarchical GAMLSS

This paper introduces a hierarchical GAMLSS framework for harmonizing and modeling neuroimaging data across multiple cohorts, showing improved removal of cohort effects and preservation of biological signals.

Associations between volumes of grey matter regions and white matter hyperintensities with cognitive empathy in oldest-old adults

The paper examines associations between grey matter volumes and white matter hyperintensities with cognitive empathy measures in oldest-old adults, finding significant links between specific brain regions and different empathy assessment methods.

An Enhanced Conditional Variational Autoencoder-Based Normative Model for Neuroimaging Analysis

This paper introduces an enhanced cVAE-based normative model for neuroimaging data, showing comparable performance to existing methods while capturing individual deviations related to hypertension severity.

Brain-Age Prediction: Systematic Evaluation of Site Effects, and Sample Age Range and Size

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

Normative Modeling of Brain Morphometry Across the Lifespan using CentileBrain: Algorithm Benchmarking and Model Optimization

The paper benchmarks and optimizes a normative modeling framework for brain morphometry across the lifespan using MFPR, showing excellent accuracy and stability.

Dissociable Cellular and Genetic Mechanisms of Cortical Thinning at Different Life Stages

The paper examines age-related variations in cortical thickness across different life stages using gene expression data from a large neuroimaging dataset.

Brain structural covariances in the ageing brain in the UK Biobank

This study examines brain structural covariances in the ageing brain using UK Biobank data, finding age-related changes in cortical thickness and subcortical volume correlations, with sex differences and associations with cognition and longevity.

Age- and sex-related topological organisation of human brain functional networks and their relationship to cognition

The paper examines age and sex effects on brain network topology in older adults and links these to cognitive performance using UK Biobank data.

Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank

This study identifies genetic variants associated with brain functional network measures in UK Biobank participants, linking them to sleep and psychiatric traits.

Cortical Thickness Trajectories across the Lifespan: Data from 17,075 healthy individuals aged 3-90 years

The paper analyzes cortical thickness trajectories in 17,075 individuals to show peak thickness in childhood, steep decline in early adulthood, and slower decline later, with notable exceptions and significant inter-individual variability.

Greater male than female variability in regional brain structure across the lifespan

The paper analyzes sex differences in brain structure variability across the lifespan using a large dataset, finding greater male variability in subcortical volumes, cortical surface area, and thickness in most regions.

Subcortical Volume Trajectories across the Lifespan: Data from 18,605 healthy individuals aged 3-90 years

This study analyzes subcortical volume changes across the lifespan using MRI data from 18,605 individuals, finding age-related declines in some structures and increases in others.

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

The paper reports epigenome-wide meta-analyses of blood DNA methylation with subcortical brain volumes, identifying significant associations with hippocampal volume and potential biological mechanisms.

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.

Planar cell polarity pathway and development of the human visual cortex

The paper identifies genetic associations with cortical surface area using PCA and GWAS, linking DAAM1 to visual cortex development through mitochondrial pathways and thalamocortical input.