Sreemathi Logan

This study identifies a ciliary gene program linked to cognitive resilience in mice, independent of age, by integrating behavioral data with transcriptomic profiling.

This study shows that soluble pathogenic tau aggregates are transmitted to astrocytes, causing mitochondrial dysfunction, senescence, and neurovascular uncoupling in a tauopathy model.

This study shows that reducing IGF-1R in adult hippocampal neurons impairs spatial learning and memory in male mice but not females, with structural changes in dendritic boutons and altered signaling pathways.