Ye Li

The paper maps serotonin autoreceptor expression in Drosophila using single-cell sequencing and genetic labeling, identifying 5-HT2A and 5-HT7 in serotonergic neurons.

The paper shows that Wnd/DLK signaling in Drosophila motoneurons is activated only when synaptic terminals are completely removed, not when they are partially spared.

The paper introduces a parallelly distributed microscope and software system for high-throughput multispectral 3D imaging with high resolution and data throughput.

The paper develops a platform for storing, visualizing, and analyzing large-scale 3D images in HPC environments using a scalable storage format and web-based annotation tools.

This study compares lossless compression methods for microscopy data, recommending BLOSC with ZSTD for optimal compression ratios across various conditions.

The paper modifies circuit parameters in Drosophila mushroom bodies to assess how changes affect odor selectivity and discrimination.

The paper introduces nCorrect, an algorithm that improves neuron tracing by reanalyzing existing traces to produce more physiologically-relevant reconstructions using a 4D minimization algorithm and a new similarity metric.

nGauge provides an extensible Python toolkit for analyzing neuron morphology data, improving data compatibility and enabling advanced analysis and visualization.

The paper uses targeted scRNA-seq and multi-informatic analysis to characterize neural differentiation in Drosophila brain neuroblast lineages and provides a visualization tool for gene function curation.

This study introduces Lineage Tracker Bitbow, a multi-spectral lineage tracing system for Drosophila, and uses it to map neuronal lineages and analyze cis-regulatory elements in lineage-specific gene expression.

The paper develops nTracer, an ImageJ plugin for reconstructing neuronal morphology in densely labeled mouse brains using multispectral tracing.