Sam Audrain

HippoGenes: A robust workflow for subregional transcriptomic profiling of the human hippocampus

HippoGenes creates transcriptomic maps of the human hippocampus using spatial statistical models and the Allen Human Brain Atlas, enabling subregional gene expression analysis and disease-related molecular decoding.

Fiber-tract development contributes to functional specialization in the human hippocampus

The paper examines how fiber-tract development in the human hippocampus correlates with functional specialization across childhood, finding that cross-sectional area of specific tracts predicts functional specialization.

Connectome-wide mega-analysis identifies a reproducible functional network signature of temporal lobe epilepsy

The paper identifies a reproducible functional connectivity signature in temporal lobe epilepsy through a large-scale connectome-wide analysis.

Single voxel autocorrelation reflects hippocampal function in temporal lobe epilepsy

This study examines how hippocampal dysfunction in temporal lobe epilepsy affects single voxel autocorrelation, finding longer intrinsic timescales in left TLE patients and a link between cluster preservation and memory performance.

Personalized Biomarkers of Multiscale Functional Alterations in Temporal Lobe Epilepsy

This study identifies patient-specific functional biomarkers in temporal lobe epilepsy using multimodal MRI data to predict clinical outcomes and guide precision therapeutics.

Leveraging the resting brain to predict memory decline after temporal lobectomy

This study predicts memory decline after temporal lobectomy using resting-state fMRI network measures, finding that left TLE patients with more abnormal memory networks and greater integration of the resected region experience greater verbal memory decline.

Schemas provide a scaffold for neocortical integration at the cost of memory specificity over time

This study uses fMRI to show that schemas facilitate faster memory consolidation by integrating representations in the medial prefrontal cortex, but at the cost of losing memory specificity over time.

A role for the anterior hippocampus in autobiographical memory construction regardless of temporal distance

The paper investigates the role of the anterior hippocampus in autobiographical memory construction across different memory ages, finding no temporal gradient during construction but strong anterior hippocampus activity regardless of memory remoteness.