Author

Shan Cheng

Capital Medical UniversityORCID 0000-0002-8658-6916Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Binwei DuaniD· 1 shared Feng LiiD· 1 shared Guoyan Zhang· 1 shared Jing WangiD· 1 shared Qiong WuiD· 1 shared Sifan Meng· 1 shared Wei DingiD· 1 shared Xiaowei Sha· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Binwei DuanORCID

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1 paper

Recent·Most cited

ZNF638 represses the transcription of HBV closed circular DNA involving HUSH complex-mediated histone modifications of epigenetic silencing

Sifan Meng, Xiaowei Sha, Guoyan Zhang, Binwei Duan, Jing Wang, Yang Si, Feng Li, Qiong Wu, Shan Cheng, Wei Ding

This study identifies ZNF638 as a host factor that represses HBV transcription by recruiting the HUSH complex to induce H3K9me3 histone modifications, thereby silencing cccDNA and reducing viral propagation.

Cell Communication and Signaling · Feb 13, 2026Peer-reviewedBiochemistry