Carine Marinach

The paper identifies vulnerable sites on the P36-P52 protein complex of Plasmodium sporozoites using structural biology and functional assays, showing that antibodies targeting these sites can neutralize SPZ invasion.

This study shows that CLIP is essential for host cell invasion by both merozoites and sporozoites of P. berghei, supporting a conserved role of the CLAMP-CLIP-SPATR complex in apicomplexan invasion.

This paper develops a new Plasmodium berghei parasite line with constitutive Cas9 and inducible Cre recombinase for conditional gene editing, demonstrating its use in knocking out the CLAMP gene.