Author

Joseph Al Haddad

Boston Children's HospitalORCID 0000-0002-8686-3151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2

Frequent Co-Authors

Eric Lieberman GreeriD· 2 shared Kejun YingiD· 2 shared M. Hafiz RothiiD· 2 shared Scarlett Dellacona· 2 shared Vadim N. GladysheviD· 2 shared Anna DongiD· 1 shared Anya Flood TayloriD· 1 shared Christiane ZorbasiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Eric Lieberman GreerORCID

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2 papers

Recent·Most cited

The 18S rRNA Methyltransferase DIMT-1 Regulates Lifespan in the Germline Later in Life

M. Hafiz Rothi, Gautam Chandra Sarkar, Joseph Al Haddad, Wayne Mitchell, Kejun Ying, Nancy K. Pohl, Roberto G. Sotomayor-Mena, Julia Natale, Scarlett Dellacona, Vadim N. Gladyshev, Eric Lieberman Greer

This study identifies DIMT-1 as a regulator of C. elegans lifespan and stress resistance through its role in rRNA methylation and germline function.

Nature Communications · Jul 28, 2025Peer-reviewedGenetics

Intergenerational hormesis is regulated by heritable 18S rRNA methylation

Noa Liberman, M. Hafiz Rothi, Maxim V. Gerashchenko, Christiane Zorbas, Konstantinos Boulias, Fiona G. MacWhinnie, Kejun Ying, Anya Flood Taylor, Joseph Al Haddad, Hiroki Shibuya, Lara Roach, Anna Dong, Scarlett Dellacona, Denis L. J. Lafontaine, Vadim N. Gladyshev, Eric Lieberman Greer

The paper tracks heritable methylation transmission in C. elegans and shows that parental starvation induces intergenerational hormesis via 18S rRNA methylation.

Molecular Cell · Sep 1, 2023Peer-reviewedGenetics