Author

Renato Elias Rodrigues de Souza Santos

Boston Children's HospitalORCID 0000-0002-8702-4202Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Paula I. WatnickiD· 2 shared Brendan J. O’HaraiD· 1 shared Chris AkutiD· 1 shared Jacob A. GibsoniD· 1 shared Jamaurie James· 1 shared John J. MekalanosiD· 1 shared Michael J. GebhardtiD· 1 shared Pallabi BasuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Paula I. WatnickORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Actuation of CRP activating region 3 by acetylation modulates V. cholerae sugar utilization and virulence

Renato Elias Rodrigues de Souza Santos, Pallabi Basu, Brendan J. O’Hara, Jacob A. Gibson, Michael J. Gebhardt, Chris Akut, William Paul Robins, John J. Mekalanos, Simon L. Dove, Paula I. Watnick

This study shows that acetylation of CRP K52 activates AR3, leading to changes in gene expression that affect sugar utilization and virulence in V. cholerae.

Proceedings of the National Academy of Sciences · Sep 10, 2026Peer-reviewedMicrobiology

Carbon source, cell density, and the microbial community control inhibition of V. cholerae surface colonization by environmental nitrate

Jamaurie James, Renato Elias Rodrigues de Souza Santos, Paula I. Watnick

This study shows that nitrite from V. cholerae nitrate respiration inhibits biofilm formation, but co-culturing with P. aminovorans reduces nitrite and enhances V. cholerae colonization.

mBio · Feb 25, 2025Peer-reviewedMicrobiology