Author

Brendan J. O’Hara

Boston Children's HospitalORCID 0000-0003-0138-2744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1 Organism:virus· 1

Frequent Co-Authors

Chris AkutiD· 1 shared Jacob A. GibsoniD· 1 shared John J. MekalanosiD· 1 shared Michael J. GebhardtiD· 1 shared Pallabi BasuiD· 1 shared Paula I. WatnickiD· 1 shared Renato Elias Rodrigues de Souza SantosiD· 1 shared Simon L. DoveiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Chris AkutORCID

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1 paper

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedSep 10, 2026

Actuation of CRP activating region 3 by acetylation modulates V. cholerae sugar utilization and virulence

Renato Elias Rodrigues de Souza Santos, Pallabi Basu, Brendan J. O’Hara…·Paula I. Watnick

This study shows that acetylation of CRP K52 activates AR3, leading to changes in gene expression that affect sugar utilization and virulence in V. cholerae.

DOI 10.1073/pnas.2602861123

virusChIP-seq

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