Simon L. Dove

Actuation of CRP activating region 3 by acetylation modulates V. cholerae sugar utilization and virulence

This study shows that acetylation of CRP K52 activates AR3, leading to changes in gene expression that affect sugar utilization and virulence in V. cholerae.

Genome-wide protein-DNA interaction site mapping using a double strand DNA-specific cytosine deaminase

This paper introduces a method called 3D-seq to map DNA-protein interaction sites in vivo using a modified cytosine deaminase, demonstrating its application in Pseudomonas aeruginosa transcription factors.

Improved transformation efficiency of group A Streptococcus by inactivation of a type I restriction modification system

This study shows that inactivating the type I restriction modification system in group A Streptococcus improves transformation efficiency.