Alexander German

Ultrastructural comparison of fixation and cryopreservation methods for brain preservation

The paper compares fixation and cryopreservation methods for brain preservation, finding that ASC with SDS permeabilization matches aldehyde perfusion in preserving tissue structure.

Functional recovery of the adult murine hippocampus after cryopreservation by vitrification

This study shows that the adult murine hippocampus can recover near-physiological function after vitrification, preserving key features like synaptic plasticity and neuronal excitability.

CRYO-CEST: Non-invasive imaging of cryoprotectants using chemical exchange saturation transfer

This study explores CEST MRI at 7T to detect and quantify cryoprotectants in organ cryopreservation, showing formamide's sensitive concentration-dependent response.

Excitability and synaptic transmission after vitrification of mouse corticohippocampal slices.

This study vitrifies and rewarms mouse corticohippocampal slices to assess synaptic transmission, finding preserved fEPSPs and HFS-induced potentiation but unstable results due to cellular alterations.