Anna Fejtová

Dissection of neuropsychiatric-relevant behavioral and structural phenotypes utilizing neuron type-specific ablation of the Bassoon gene in mice

This study investigates the effects of Bassoon gene ablation in specific mouse neuron populations on behavioral and structural phenotypes resembling schizophrenia.

Bassoon is required for adult ocular dominance plasticity and experience-induced changes in synapsin phosphorylation in visual cortex

This study shows that bassoon is essential for adult ocular dominance plasticity but not juvenile plasticity, involving presynaptic changes in synapsin phosphorylation.

Autism-like behavior induced by conditional ablation of the Bassoon gene in GABAergic interneurons

This study shows that conditional ablation of the Bassoon gene in GABAergic interneurons leads to autism-like behaviors and synaptic dysfunction in mice.

Functional recovery of the adult murine hippocampus after cryopreservation by vitrification

This study shows that the adult murine hippocampus can recover near-physiological function after vitrification, preserving key features like synaptic plasticity and neuronal excitability.

Role of Bassoon-mediated active zone integrity at different types of brain synapses for brain activity and cortex-dependent memory formation

This study investigates the role of Bassoon in different synapse types by generating conditional knockout mice, finding distinct effects on brain activity and learning.

Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity

The paper shows that neuronal activity triggers brevican cleavage via proteolytic cascades, enabling structural synaptic plasticity in the rat hippocampus.

Developmental effect of RASopathy mutations on neuronal network activity on a chip

This study examines how RASopathy mutations affect neuronal network activity in cultured neurons from mouse models, revealing developmental phenotypes and persistent network differences.

Neural Extracellular Matrix Remodeling Signatures in Genetic and Acquired Mouse Models of Epilepsy

The paper investigates ECM remodeling in different epilepsy models and identifies ECM components that predict seizure properties.

Bassoon controls synaptic vesicle pools via regulation of presynaptic phosphorylation and cAMP homeostasis

This study identifies bassoon's role in regulating synaptic vesicle pools through presynaptic phosphorylation and cAMP homeostasis, revealing its impact on neurotransmitter release.

Nanoscopical analysis reveals an orderly arrangement of the presynaptic scaffold protein Bassoon at the Golgi-apparatus

The paper uses STED nanoscopy to show Bassoon is an extended protein at the Golgi-apparatus with its N-terminus near the trans-Golgi network and C-terminus away from it.