Christian Alzheimer

This study investigates the molecular interactions between KCNQ1, KCNE1, and BACE1 using multiple assays, revealing domain-specific contributions and functional additivity.

This study shows that the adult murine hippocampus can recover near-physiological function after vitrification, preserving key features like synaptic plasticity and neuronal excitability.

This study investigates BACE1's role in sleep-wake cycles through enzymatic and non-enzymatic actions using mouse models, finding altered sleep patterns and EEG characteristics in mutants.

This study shows artemisinins inhibit pyridoxal kinase, disrupting GABAergic signaling by reducing PLP production and affecting glutamic acid decarboxylase activity.