Author

Yunpeng Huang

Chinese University of Hong KongORCID 0000-0002-8710-9062Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Bowen MaiD· 2 shared B. K.W. NG· 1 shared Dean W. FelsheriD· 1 shared Haixing XuiD· 1 shared Jialin LiuiD· 1 shared Khadija Shahed KhaniD· 1 shared Shuhui JiiD· 1 shared Tongyang XuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Bowen MaORCID

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2 papers

Recent·Most cited

Rewiring c-Myc Transcriptional Activity with an O-GlcNAcylation Targeting Chimera (OGTAC)

Tongyang Xu, Zhihao Guo, Khadija Shahed Khan, Yunpeng Huang, Bowen Ma, Shuhui Ji, Jialin Liu, Dean W. Felsher, B. K.W. NG

This paper introduces OGTAC, a molecule that enhances c-Myc O-GlcNAcylation, rewires its transcriptional activity, and inhibits cancer cell proliferation.

Cell chemical biology · Sep 1, 2026Peer-reviewedBiochemistry

Proximity-induced protein deglycosylation by endogenous O-GlcNAcase

Haixing Xu, Bowen Ma, Yunpeng Huang, Wai‐Lung Ng

This paper introduces DOGTACs, a method to selectively remove O-GlcNAc from target proteins using endogenous OGA in living cells, showing concentration- and time-dependent de-O-GlcNAcylation without affecting global O-GlcNAc levels.

bioRxiv · Aug 26, 2026 · PreprintCell Biology