Collin Joyce

The paper analyzes changes in the human antibody repertoire over four years using high-throughput sequencing, finding conservation of broad features but changes in fine details.

This study improves HIV broadly neutralizing antibodies through multistate engineering, resulting in enhanced breadth and potency against diverse Env variants.

This study immunized cows with HIV Env trimers to generate broadly neutralizing antibodies targeting the V2-apex, revealing ultralong CDRH3 antibodies outcompete shorter ones in the response.