Mateusz Kędzior

Engineering HIV antibodies with enhanced breadth and potency of neutralization through multistate affinity maturation

This study improves HIV broadly neutralizing antibodies through multistate engineering, resulting in enhanced breadth and potency against diverse Env variants.

Improvement of affinity and potency of a monoclonal antibody against Shigella flexneri 3a O-antigen via phage display and whole-cell in-solution panning

This paper improves the affinity and potency of a monoclonal antibody against Shigella flexneri 3a O-antigen using phage display and whole-cell panning, showing enhanced antibacterial activity and broader serotype recognition.

A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.