Author

Ramón Gimeno

Hospital Del MarORCID 0000-0002-8758-121XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ariadna Acedo-TerradesiD· 2 shared Estela PradaiD· 2 shared Evelyn AndradesiD· 2 shared Inmaculada Hernández‐MuñoziD· 2 shared Irene CuervasiD· 2 shared Jaume MoraiD· 2 shared Júlia Perera‐BeliD· 2 shared Marta Bódalo‐TorruellaiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Ariadna Acedo-TerradesORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 17, 2026

RERE and the Mediator complex cooperate with EWSR1::FLI1 in the reprogramming of Translation and Alternative Splicing, the latter being a therapeutically targetable vulnerability in Ewing sarcoma

Irene Cuervas, Sophie Bonnal, Evelyn Andrades…·Inmaculada Hernández‐Muñoz

This paper identifies MED13L and RERE as genes regulated by EWSR1::FLI1 in Ewing sarcoma, showing their role in altering translation and alternative splicing, and demonstrates RBM39 inhibition as a therapeutic strategy.

DOI 10.64898/2026.08.13.744586

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 13, 2025

EWS-FLI1 Expression in Human Embryonic MSCs Leads to Transcriptional Reprograming, Defective DNA Damage Repair and Ewing Sarcoma

Inmaculada Hernández‐Muñoz, Irene Cuervas, Estela Prada…·Jaume Mora

This study shows that EWS-FLI1 expression in human embryonic mesenchymal stem cells leads to an ES-like transcriptome and tumor formation, despite not preferentially binding promoters.

1 citation

humanscRNA-seq

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