Estela Prada

This paper identifies MED13L and RERE as genes regulated by EWSR1::FLI1 in Ewing sarcoma, showing their role in altering translation and alternative splicing, and demonstrates RBM39 inhibition as a therapeutic strategy.

This study identifies USP7 as a critical regulator of PAX3::FOXO1 enhancers in FP-RMS and shows its inhibition reduces tumor growth.

This study shows that EWS-FLI1 expression in human embryonic mesenchymal stem cells leads to an ES-like transcriptome and tumor formation, despite not preferentially binding promoters.