Identification of molecular pathways involved in the anti-liver cancer activity of madecassic acid
Geraud N. Sansom, Emily P. Friar, David Shorthouse, Thao Thi Phuong Tran, Fernando J. Sialana, Đỗ Thị Thảo, Trần Văn Chiến, Yen Thi Hoang Be, Trần Văn Sung, Michelle Dawn Garrett, Christopher J. Serpell
This study identifies molecular pathways of madecassic acid's anti-liver cancer activity using chemical proteomics and RNAseq, showing its interactions with proteins related to metabolism and nucleic acid processing.
bioRxiv · Aug 17, 2025 · PreprintPharmacology & Toxicology