Author

Bushra Memon

Hamad bin Khalifa UniversityORCID 0000-0002-8766-2570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Essam Mohamed AbdelalimiD· 2 shared Noura AldousiD· 2 shared Sadaf Ijaz· 2 shared Sikander HayatiD· 2 shared Ahmed K. ElsayediD· 1 shared Ahmed Kamel ElsayediD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 14 mutual co-author links

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2 shared papersDevelopmental Biology

Essam Mohamed AbdelalimORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 18, 2024

RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells

Bushra Memon, Noura Aldous, Ahmed K. Elsayed…·Essam Mohamed Abdelalim

This study investigates RFX3's role in human pancreatic islet development using iPSC-derived organoids, finding that RFX3 loss disrupts endocrine cell differentiation and beta-cell function.

DOI 10.1101/2024.09.18.613711

humanscRNA-seq

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Developmental BiologybioRxivPreprintMar 6, 2024

Deletion of RFX6, a Diabetes-Associated Gene, Impairs iPSC-Derived Islet Organoid Development and Survival, With No Impact on the Generation of PDX1+/NKX6.1+ Progenitors

Noura Aldous, Ahmed Kamel Elsayed, Bushra Memon…·Essam Mohamed Abdelalim

This study shows that RFX6 deletion in iPSCs impairs islet organoid development and survival through apoptosis and gene downregulation, without affecting PDX1+/NKX6.1+ progenitors.

DOI 10.1101/2024.03.06.583663

humanscRNA-seq

𝕏 PostBluesky