Imputed graph-genotyped structural variants identify regulatory haplotypes associated with gene expression in Atlantic salmon
Maëlys Chapis, Domniki Manousi, Célian Diblasi…·Marie Saitou
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Norwegian University of Life SciencesORCID 0000-0002-8794-3217Unclaimed ORCID profile · follow to get notified of new preprints
18 papers
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Maëlys Chapis, Domniki Manousi, Célian Diblasi…·Marie Saitou
Célian Diblasi, Jun Soung Kwak, Domniki Manousi…·Marie Saitou
The paper investigates the evolutionary origins of shared structural variants across Atlantic salmon lineages, finding they result from ancient persistence, recurrent mutation, and lineage-specific frequency changes.
This study evaluates a course redesign in a graduate genomics course, finding improved perceived navigability but persistent challenges in course coherence.
Marie Saitou, Louise Chavarie, Thrond Oddvar Haugen
This study shows that no-take zones in linear coastal systems improve population recovery when aligned with larval dispersal direction, but their effectiveness depends on spatial placement and dispersal patterns.
Erik Sandertun Røed, Charlie D. Ellis, Jamie R. Stevens…·Marie Saitou
The paper evaluates a SNP panel's ability to detect hybridization across generations in European lobsters using resampling-based methods and empirical data.
This study compares gene expression in human breast tissue with other epithelial secretory tissues to identify conserved and tissue-specific regulatory programs.
Célian Diblasi, Domniki Manousi, David G. Hazlerigg…·Marie Saitou
The paper analyzes eQTL data in Atlantic salmon to show long-term dosage balance maintenance after a 100 million-year-old genome duplication.
Domniki Manousi, Shahmir Naseer, Samuel Martín…·Marie Saitou
This study examines the evolution of gig immune genes in teleosts, focusing on Atlantic salmon, revealing distinct evolutionary trajectories and regulatory mechanisms.
Marie Saitou, Domniki Manousi, Jayme van Dalum…·Simen R. Sandve
The paper identifies a major locus on chromosome 14 associated with gill gene expression and somatic growth in Atlantic salmon during smoltification.
Sonja Trebing, Matthias Freund, Anda L. Iosip…·Ines Kreuzer
This study identifies impaired cell wall biomechanics as the cause of delayed trap closure in the Venus flytrap mutant DYSCALCULIA, linking mechanosensing and Ca2+ signaling to trap kinetics.
Alber Aqil, Yanyan Li, Zhiliang Wang…·Naoki Masuda
The paper identifies switch-like genes across multiple tissues and links their expression patterns to disease susceptibility, finding tissue-specific and universally switch-like genes with potential therapeutic implications.
Marie Saitou, Arturo Vera-Ponce de León, Akira Harding…·Lars Gustav Snipen
The paper analyzes unmapped reads from Atlantic salmon RNA-seq to detect microbial signals, finding tank-specific effects but no survival or sex associations.
Pauline Buso, Célian Diblasi, Domniki Manousi…·Marie Saitou
The paper examines genomic responses to domestication in Atlantic salmon, revealing parallel selection on MHC genes and WGD-derived homeologous regions.
Marie Saitou, Andy W. Dahl, Qingbo Wang, Xuanyao Liu
The paper investigates how allele frequency differences of causal variants impact PRS portability between European and African populations, finding they significantly reduce accuracy.
Marie Saitou, Naoki Masuda, Ömer Gökçümen
The paper identifies adaptive genomic structural variants across 26 populations using a network-based method and finds 577 variants with high population distribution, some overlapping with coding sequences or GWAS traits.
Marie Saitou, Eliza A. Gaylord, Erica Xu…·Ömer Gökçümen
The paper identifies the origins of salivary proteins and reveals gene repertoires specific to fetal and adult salivary glands, showing functional diversity is driven by transcriptional regulators.
The paper identifies insertion sites of polymorphic duplications and finds a HERC2 haplotype under selection in European populations.
Marie Saitou, Yoko Satta, Ömer Gökçümen
The paper investigates the evolutionary history of the GSTM1 gene deletion in East Asian populations, finding evidence of a soft sweep and its association with disease susceptibility.