Author

O’Neil Wiggan

Colorado State UniversityORCID 0000-0002-8795-0716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Adam C Koch· 1 shared Ashok PrasadiD· 1 shared Brian J. GeissiD· 1 shared Christopher Davis SnowiD· 1 shared Emry Burns· 1 shared Renzo Spagnuolo· 1 shared Rosaline A. Danzman· 1 shared Sebastian Lawton· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adam C Koch

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Live-cell, single-molecule imaging resolves the dual nature of mRNA silencing by SARS-CoV-2 Nsp1

Adam C Koch, O’Neil Wiggan, Emry Burns, Brian J. Geiss, Christopher Davis Snow, Timothy J. Stasevich

This study uses live-cell imaging to show SARS-CoV-2 Nsp1 silences mRNAs by reducing their numbers through two cap-dependent mechanisms, while viral UTRs enhance translation but do not protect from Nsp1.

bioRxiv · Oct 30, 2026 · PreprintMolecular Biology

Cell Morphology accurately predicts the nuclear shape of adherent cells

Sebastian Lawton, Rosaline A. Danzman, Renzo Spagnuolo, Skylar Stephan, Sydney Graul, O’Neil Wiggan, Soham Ghosh, Ashok Prasad

The paper trains a model to predict nuclear shape from cell shape and shows that actomyosin contractility influences nuclear morphology.

bioRxiv · Dec 28, 2024 · PreprintCell Biology