Dominik Lutter

This study uses an oral protein tolerance test combined with metabolomics to show that sarcopenic older adults have slower postprandial decline in essential amino acids compared to young controls, suggesting altered anabolic sensitivity.

This study uses single nucleus RNA sequencing to analyze cortical and striatal development in a mouse model of Allan-Herndon-Dudley Syndrome, identifying disruptions in oligodendrocyte lineage, cell-cell communication, and cilia formation.

This study shows that neural CXCR4 reduces atherosclerotic plaque formation in mice without affecting metabolism or immune cells, and identifies MIF-CXCR4 signaling in the PVN as a potential neuroimmune pathway in atherosclerosis.

The paper identifies Dpp4+ preadipocytes in pre-wean mice and shows Igf2 promotes their expansion, which drives adipogenesis.

This study shows that a hypercaloric diet causes temporary molecular changes in astrocytes specifically in the arcuate nucleus of the hypothalamus.

CoNI integrates multi-omics data to identify genetic regulators of hepatic metabolism, validating several candidates in human liver cells and biopsies.

This study identifies plasma proteins associated with the placebo effect in nausea using proteomics and shows they predict placebo response.